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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5R2
All Species:
15.15
Human Site:
S89
Identified Species:
37.04
UniProt:
Q13319
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13319
NP_003927.1
367
38705
S89
K
V
T
P
K
P
A
S
T
G
P
D
P
L
V
Chimpanzee
Pan troglodytes
XP_516099
367
38658
S89
K
V
T
P
K
P
A
S
T
G
P
D
P
L
V
Rhesus Macaque
Macaca mulatta
XP_001113074
307
34072
K62
I
V
A
V
S
A
K
K
K
N
S
K
K
V
Q
Dog
Lupus familis
XP_853120
458
47635
S177
K
V
T
P
K
P
A
S
T
G
P
D
P
L
V
Cat
Felis silvestris
Mouse
Mus musculus
O35926
369
38896
S89
K
V
T
P
K
P
A
S
T
G
P
D
P
L
V
Rat
Rattus norvegicus
P61810
307
34013
K62
I
V
A
V
S
A
K
K
K
N
S
K
K
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089375
320
35634
K75
A
K
K
K
N
A
K
K
I
N
P
N
P
G
P
Zebra Danio
Brachydanio rerio
NP_001017569
308
34577
P62
K
S
A
K
K
V
N
P
N
P
P
V
A
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22695
356
39856
S80
R
S
L
P
K
S
G
S
S
S
E
A
T
S
S
Sea Urchin
Strong. purpuratus
XP_794538
375
41683
D91
G
V
S
T
T
S
L
D
T
N
F
N
S
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
49.5
77.2
N.A.
94.3
48.7
N.A.
N.A.
N.A.
58.3
55.5
N.A.
N.A.
N.A.
31.6
36.5
Protein Similarity:
100
99.7
59.1
77.7
N.A.
94.8
58.5
N.A.
N.A.
N.A.
64.5
64.8
N.A.
N.A.
N.A.
42.5
49.8
P-Site Identity:
100
100
6.6
100
N.A.
100
6.6
N.A.
N.A.
N.A.
13.3
20
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
100
100
13.3
100
N.A.
100
6.6
N.A.
N.A.
N.A.
20
26.6
N.A.
N.A.
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
30
0
0
30
40
0
0
0
0
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
40
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
10
0
0
40
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
50
10
10
20
60
0
30
30
20
0
0
20
20
0
10
% K
% Leu:
0
0
10
0
0
0
10
0
0
0
0
0
0
40
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
10
0
10
40
0
20
0
0
0
% N
% Pro:
0
0
0
50
0
40
0
10
0
10
60
0
50
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
20
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
20
10
0
20
20
0
50
10
10
20
0
10
20
10
% S
% Thr:
0
0
40
10
10
0
0
0
50
0
0
0
10
0
0
% T
% Val:
0
70
0
20
0
10
0
0
0
0
0
10
0
10
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _